Characterisation of the interaction between material and cells by determining degradation and biocompatibility of metallic biomaterials and implant prototypes
Assessment of the effects of degradable metallic biomaterials, for example, on the differentiation and reactivity of mesenchymal stem cells with a focus on osteogenic, chondrogenic and neuronal lineages
Establishment of complex cell (co)-culture models to simulate physiological and pathological conditions, e.g. bone/cartilage degeneration, inflammation, cancer, neurological diseases
Application of these models to determine the influence of metallic biomaterials on tissue regeneration and healing
Experimental approaches to create data sets that can be used for mathematical simulation and modeling of biological processes such as bone healing
Verification of data from preclinical studies and validation of models of biological processes
