Investigation  of antibacterial activity and polyethersulfone (PES) membrane usability of delafossite‑type CuMnO₂ and CuMnO₂‑NH₂ nanostructures

Membrane fouling is one of the most important issues in membrane studies and remains a current challenge. Therefore, developing composite membranes to reduce fouling is essential. In this study, delafossite-type CuMnO₂ and CuMnO₂-NH₂ nanostructures were synthesized and characterized in detail using various instrumental tools, including SEM, SEM-Elemental Mapping, P-XRD, BET, and FTIR. The biological properties of CuMnO₂ and CuMnO₂-NH₂ nanostructures, including antioxidant, antimicrobial, cell viability, antidiabetic activity, antibiofilm activity, and DNA fragmentation, were examined. Both materials exhibited good antioxidant, antimicrobial, and antibiofilm properties. The highest antioxidant activity for CuMnO₂ was 75.93% at 100 mg/L, while the highest antioxidant activity for CuMnO₂-NH₂ was 92.35% at 100 mg/L. The most effective MIC value of 16 mg/L was obtained for CuMnO₂ against Enterococcus hirae and Enterococcus faecalis. The highest amylase activity, at 165.2%, was observed at 100 mg/L for CuMnO₂. Both CuMnO₂ and CuMnO₂-NH₂ exhibited complete inhibition of microbial cell viability (100%) at 100 mg/L. Additionally, they demonstrated excellent biofilm inhibition activities against S. aureus and P. aeruginosa. Furthermore, the use of polyethersulfone (PES) membranes coated with CuMnO₂ and CuMnO₂-NH₂ compounds for the eradication of Escherichia coli was investigated, along with the antibacterial activities of the membrane surface and permeate.